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mecfs_bio.assets.gwas.myocardial_infarction.raw.raw_mi_data

Raw Summary Statistics from the Million Veterans Program GWAS of myocardial infraction

See here for the ftp download page: https://ftp.ebi.ac.uk/pub/databases/gwas/summary_statistics/GCST90475001-GCST90476000/GCST90475932/harmonised/

See the GWAS catalog page here: https://www.ebi.ac.uk/gwas/studies/GCST90475932

The causal chain LDL -> Atherosclerosis -> Myocardial Infarction is well-established, and thus can serve as a positive control for the detection of causal pathways. That is, any causal pathway detection method should be able to detect this pathway.

Attributes:

MILLION_VETERAN_MI_EUR_DATA_RAW module-attribute

MILLION_VETERAN_MI_EUR_DATA_RAW = DownloadFileTask(
    meta=GWASSummaryDataFileMeta(
        id=AssetId("million_veterans_mi_eur_raw"),
        trait="myocardial_infaction",
        project="million_veterans",
        sub_dir="raw",
        project_path=PurePath("GCST90475932.tsv.gzip"),
        read_spec=DataFrameReadSpec(
            format=DataFrameTextFormat(separator="\t")
        ),
    ),
    url="https://ftp.ebi.ac.uk/pub/databases/gwas/summary_statistics/GCST90475001-GCST90476000/GCST90475932/harmonised/GCST90475932.h.tsv.gz",
    md5_hash="ddf8704acb4732834013fd907dc9fa60",
)